12,834 Colon Ca Patients: Wrong Design, Wrong Question!

At the 2017 ASCO annual meeting, Qian Shi, PhD, from Mayo Clinic in Rochester, Minnesota, presented a combined individual-patient analysis of 6 studies conducted around the world, looking at 6 versus 3 months of adjuvant chemotherapy for node-positive colon cancer.¹ Despite enrolling almost 13,000 subjects, the results remain equivocal. Overall, the analysis failed to exclude a 5% chance that longer therapy improves 3-year