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MARCH 10, 2016

Vogl, NY: Adjuvant Denosumab To Prevent Fractures–At Least!

EDITORIAL BOARD
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Steven Vogl, MD
Medical Oncologist
New York City

The ABCSG-18 trial demonstrates that every breast cancer patient being offered adjuvant aromatase inhibitor (AI) therapy should be offered denosumab as well. There are 2 issues involved, either of which would mandate a discussion of using denosumab: One is prevention of fractures not related to cancer, and the other is the prevention of breast cancer relapse.

ABCSG-18 is a large prospective, double-blind, placebo-controlled