In contrast to what had previously been thought, BRAF V600E mutation in well-differentiated thyroid cancer (WDTC) is as common in children as in adults, according to investigators in California.
The single-center, retrospective study, published in Thyroid (2016;26[2]:227-234, PMID: 26649796), is the first study to simultaneously examine four major mutation types in a pediatric population, using thyroidectomy-obtained thyroid tissue from histologically confirmed WDTC, the