CheckMate 9ER Trial: ICI Provides Survival Benefit in Renal Cell Carcinoma

Relative to the previous standard of sunitinib, a combination of the checkpoint inhibitor nivolumab and the ...

DECEMBER 4, 2020

Keytruda Gains 2 New First-Line Indications: NSCLC and RCC

The FDA approved pembrolizumab (Keytruda, Merck) for the first-line treatment of patients with stage III/IV ...

APRIL 24, 2019

First-Line Avelumab-Axitinib Combo Increases PFS for Patients With Advanced RCC

First-line treatment combining the immune checkpoint blocker avelumab (Bavencio, EMD Serono/Pfizer) with the ...

JANUARY 24, 2019

Atezolizumab With Bevacizumab Ups PFS in PD-L1-Positive Advanced RCC Patients

First-line treatment with atezolizumab plus bevacizumab results in better PFS in programmed death-ligand 1 ...

DECEMBER 15, 2017

The Case for TKI Monotherapy in mRCC

Tyrosine kinase inhibitor monotherapy still has a place in front-line therapy in patients with mRCC, according to a ...

NOVEMBER 28, 2017

FDA Expands Sutent Approval to Include Post-Nephrectomy Adjuvant Rx

The FDA approved adjuvant treatment with sunitinib (Sutent, Pfizer) for adults at high risk for a recurrence of ...

NOVEMBER 17, 2017

Nivolumab Reduces Brain Tumor Volume in Some RCC Patients

Preliminary data from a small group of patients with renal cell carcinoma and brain metastases show that nivolumab ...

NOVEMBER 3, 2017

Early Data: IL-10 + Nivolumab May Improve Efficacy in Renal Cancer

Combining a pegylated interleukin-10 and an anti–PD-1 led to a partial response in 41% of patients with renal ...

OCTOBER 20, 2017

Peri-Nephrectomy Sunitinib Safe, Effective in mRCC Patients

Sunitinib is safe and as effective as neoadjuvant and adjuvant treatment for patients with metastatic renal cell ...

OCTOBER 19, 2017

Cabozantinib Improves PFS in Advanced RCC

Cabozantinib can improve PFS in patients with previously untreated advanced or metastatic RCC, according to updated ...

SEPTEMBER 21, 2017

Marital Status, Gender Influence RCC Treatment and Outcomes

The marital status and gender of patients with RCC affects the type of treatment they receive, with widowed and ...

SEPTEMBER 4, 2017

Study Supports Nivo-Ipi Combo Over Monotherapy for mRCC

The combination of nivolumab and ipilimumab may be more effective for treating metastatic renal cell carcinoma ...

AUGUST 17, 2017