GVHD
FDA Approves Niktimvo for Chronic Graft-Versus-Host Disease
The FDA has approved axatilimab-csfr (Niktimvo, Incyte Corporation) for the treatment of chronic graft-versus-host ...
AUGUST 15, 2024

New Approvals For GVHD Expand Treatment Options
For years, therapeutic options for graft-versus-host disease had been limited. Now that there are new choices, ...
DECEMBER 19, 2022

New Pediatric Indication for Ibrutinib Granted to Treat GVHD
The FDA granted a new indication for Imbruvica for children 12 months of age and older with cGVHD after failure of ...
AUGUST 25, 2022

Decreased Microbiome Diversity After HCT Associated With GVHD, Mortality
A prospective analysis confirms earlier retrospective work showing there is an association between microbiome ...
NOVEMBER 19, 2021

Jakafi Approved To Treat Chronic GVHD in Adults and Children
The FDA approved ruxolitinib (Jakafi, Incyte) for chronic graft-versus-host disease after failure of one or two ...
OCTOBER 14, 2021

Abatacept Cuts Acute GVHD Risk in Phase 2 Study
The rheumatoid arthritis drug abatacept combined with standard graft-versus-host disease (GVHD) prevention reduced ...
JUNE 22, 2021

Oral JAK Inhibitor Shows Efficacy for Steroid-Refractory Graft-Versus-Host Disease
The oral JAK inhibitor ruxolitinib is associated with significant clinical improvement in patients with ...
JANUARY 26, 2021

FDA Approves Jakafi to Treat Acute GVHD
The FDA granted a new indication for Jakafi to treat steroid-refractory acute graft-versus-host disease in adults ...
MAY 28, 2019

Low-Dose IL-2, Abatacept Show Benefit in GVHD
Researchers are making progress in efforts to combat the dangerous, often deadly, graft-versus-host disease that ...
JANUARY 22, 2018

FDA Approves Imbruvica to Treat Adults With Chronic GVHD
Imbruvica becomes the first and only therapy specifically approved for adults with cGVHD, a serious and ...
AUGUST 8, 2017

New Agent Promising for Steroid-Refractory GvHD
Begelomab, an immunoglobulin G2b monoclonal antibody against CD26, was more effective than currently ...
JANUARY 5, 2017
Graft-Versus-Host Disease Significantly Lower With Cord Blood Transplant
The incidence of chronic graft-versus-host disease among adult patients who undergo double cord blood transplants ...
AUGUST 9, 2016