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CML

FDA Grants Accelerated Approval to Scemblix for Newly Diagnosed Chronic Myeloid Leukemia

The FDA granted accelerated approval to asciminib (Scemblix, Novartis AG) for adult patients with newly diagnosed ...

OCTOBER 30, 2024

FDA Approves Scemblix to Treat Ph-Positive CML in Chronic Phase

The FDA granted accelerated approval for use of asciminib (Scemblix, Novartis) in the treatment of patients with ...

NOVEMBER 8, 2021

Earlier Molecular Testing May Boost CML Response

In chronic myelogenous leukemia (CML) patients taking a tyrosine kinase inhibitor (TKI), earlier initiation of ...

APRIL 9, 2019

Early Evaluation of Response to TKI Rx May Improve CML Outcomes

Denver—In chronic myelogenous leukemia (CML) patients taking a tyrosine kinase inhibitor (TKI), earlier ...

APRIL 30, 2018

Trial Compares Bosutinib and Imatinib for First-Line CML Rx

Chicago—A Phase III head-to-head trial of bosutinib and imatinib for first-line treatment of chronic myeloid ...

SEPTEMBER 21, 2017

Strategies for Stopping TKIs in CML Growing Clearer

San Diego—In patients with CML, longer treatment duration is associated with an increase in the odds ratio ...

MARCH 14, 2017

Iclusig Granted Approval and Label Update for CML

Ponatinib is fully approved to treat adult patients with chronic phase, accelerated phase, or blast phase chronic ...

NOVEMBER 29, 2016

ABCB1 Overexpression Predicts Poor Imatinib Response in CML Patients

High expression of ABCB1 predicts a poor response to imatinib among patients with chronic myeloid leukemia

AUGUST 9, 2016

Generic Imatinib Posed As Most Cost-Effective Initial CML Strategy

Using generic imatinib and then switching to other tyrosine kinase inhibitors (TKIs) if intolerance or lack of ...

JUNE 14, 2016

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