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JULY 14, 2025

Study Links Severity of Obesity to Elevated Risk for BE and Esophageal Cancer


The risk of developing Barrett’s esophagus and esophageal adenocarcinoma (EAC) increases with severity of obesity, according to a new study presented at DDW 2025.

Obesity is a well-known risk factor for gastroesophageal reflux disease, but a retrospective study of 906,023 patients over a decade found that individuals with both obesity and GERD have an even higher risk of developing BE and EAC (abstract Su1316). Although the link between increasing body mass index and cardiovascular disease