As genetic testing is fast becoming a defining aspect of cancer care prevention, treatment and recurrence monitoring, its role is becoming more apparent in gastroenterology, according to N. Jewel Samadder, MD, MSc, a professor of medicine at Mayo Clinic Arizona, in Phoenix.
Approximately 10% to 15% of colorectal cancers are clearly hereditary, with mutations in single genes that predispose a person to the development of these cancers. Important monogenic CRC syndromes include Lynch syndrome,