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MARCH 11, 2014

The Large, Long, Expensive ‘Definitive’ Clinical Trial

Can’t we do better?

EDITORIAL BOARD
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Maurie Markman, MD
Senior Vice President of Clinical Affairs and National Director for Medical Oncology, Cancer Treatment Centers of America, Philadelphia

Arecently reported Phase III trial that examined the utility of intermittent versus continuous androgen deprivation therapy for metastatic prostate cancer provides the background for this commentary. Before proceeding, I’d like to make clear that the intent of this all-too-brief discussion is not to