Blood clots appear to form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought, according to a preclinical multicenter study.
Clots are the second leading cause of death among cancer patients with advanced disease or aggressive tumors. While blood clots usually form to stop a wound from bleeding, cancer patients can form clots without injury, plugging up vessels and cutting off circulation to organs (Cell 2025 Feb 11.