Ayman Saad, MD
University of Alabama

Impaired cellular and humoral immune response after allogeneic hematopoietic cell transplantation (allo-HCT) is often associated with viral infection and reactivation.1 Vulnerability to viral infection varies at different post-transplant time intervals.2 For example, although herpes simplex virus (HSV) can occur at any time after HCT, cytomegalovirus (CMV) reactivation/infection is more common after engraftment and varicella-zoster virus