A haploidentical related donor may be a better choice than a matched unrelated donor (MUD) for hematopoietic cell transplant (HCT) in acute myeloid leukemia (AML) or lymphoma, according to two large registry studies and several single-center studies. A comprehensive review showed outcomes of haploidentical HCT to be comparable to MUD HCT, and the risk for graft-versus-host disease (GVHD) was lower.
Stefan O. Ciurea, MD
It is too soon to declare haploidentical HCT a standard when