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APRIL 15, 2017

Rituximab After Auto-HCT Prolongs Survival in MCL

San Diego—In younger patients with mantle cell lymphoma (MCL) who have received an autologous hematopoietic cell transplant (auto-HCT) after an induction regimen, rituximab maintenance significantly improves outcomes including overall survival (OS), according to the multicenter Phase III LyMa trial.

“Rituximab [Rituxan, Genentech] maintenance has already been shown to prolong OS in elderly MCL patients after R-CHOP [rituximab plus cyclophosphamide, doxorubicin, vincristine,