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DECEMBER 29, 2016

Niraparib Extends PFS After Chemo in Ovarian Cancer

Report From ESMO 2016 Congress:

Copenhagen, Denmark—Substantial gains in progression-free survival (PFS) can be achieved when patients with platinum-sensitive recurrent ovarian cancer are placed on maintenance therapy with niraparib, according to results of a multinational Phase III trial.

The overall population—with or without BRCA mutations, positive or negative for homologous recombination deficiency (HRD)—“achieved a clinically significant improvement in PFS,” reported Mansoor R. Mirza, MD,