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AUGUST 9, 2016

Pembrolizumab Approved for Head and Neck Cancer

Drug: Pembrolizumab (Keytruda, Merck)

Status: Approved for the treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) with disease progression on or after platinum-containing chemotherapy

Significant Data:

  • Based on a multicenter, nonrandomized, open-label, multicohort Phase Ib study of 192 patients with recurrent or metastatic HNSCC
  • Patients were enrolled regardless of tumor human papillomavirus (HPV) status (HPV-positive, 33%) 
  • The data showed an