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AUGUST 2, 2017

Acalabrutinib Granted Breakthrough Therapy Designation for MCL

Drug: Acalabrutinib (AstraZeneca/Acerta Pharma)

Status: Granted breakthrough therapy designation for treatment of patients with mantle cell lymphoma (MCL) who have received at least one previous therapy

Significant Information:

  • Acalabrutinib is a highly selective, potent Bruton tyrosine kinase (BTK) inhibitor
  • Under development for treatment of multiple B-cell cancers
  • Data on use of acalabrutinib collected through a Phase II ACE-LY-004 clinical trial conducted with patients who have relapsed or