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MARCH 23, 2017

FDA Approves First Treatment for MCC

Drug: Bavencio (Avelumab, EMD Serono)

Status: Approved for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy

Significant Information:

  • Targets the PD-1/PD-L1 pathway
  • Based on data from the Phase II JAVELIN Merkel 200 study
  • Of the 88 patients who received avelumab in the trial, 33% experienced complete or partial shrinkage of their tumors
  • The response lasted for more than 6 months in