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MARCH 30, 2017

CAR-T Therapy Granted Priority Review for B-Cell ALL

Drug: CTL019 (tisagenlecleucel-T, Novartis)

Status: Granted priority review for the treatment of relapsed and refractory pediatric and young adult patients with B-cell acute lymphoblastic leukemia

Significant Information:

  • Investigational chimeric antigen receptor T-cell (CAR-T) therapy
  • Based on the results from the Phase II ELIANA study
  • 82% (41/50) of patients infused with CAR-T therapy achieved complete remission or complete remission with incomplete blood count recovery at three months