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MARCH 2, 2017

FDA Grants Orphan Drug Designation to EDV Nanocells for GBM

Drug: Epidermal growth factor receptor (EGFR)-targeted, doxorubicin-loaded EDV nanocells (EnGeneIC)

Status: Granted orphan drug designation for the treatment of glioblastoma multiforme

Significant Information:

  • A nanoparticle drug platform designed to directly target and kill tumor cells with minimal toxicity, while stimulating the immune system’s natural antitumor response
  • Intravenously injected EDV nanocells exit the leaky vascular system found within tumors and attach to cancer cells via a