×
ADVERTISEMENT

APRIL 1, 2016

Study Evaluates Potential Roles of Methylnaltrexone in Cancer Patients

Drug shows possible OS benefits in addition to laxative effects

San Diego—Methylnaltrexone, a peripherally acting μ-opioid receptor (MOR) antagonist, may play a role in slowing tumor progression, new research has found. According to the study, methylnaltrexone influenced cancer progression and prolonged survival in patients with advanced cancer, suggesting that the MOR  may be an important therapeutic target.

“Our data suggest that methylnaltrexone used in advanced cancer patients treated with opioids is associated with prolonged