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MARCH 28, 2025

Guidelines Sought for Managing Risks of Long-Term Opioid Therapy Discontinuation


Originally published by our sister publication Pain Medicine News

Long-term opioid therapy (LTOT) is common in the United States to help patients manage pain. However, there is a lack of practical clinical guidelines for vulnerable LTOT patients, where continuing therapy or tapering to discontinuation poses risks.

A team led by Christine Timko, PhD, from the Center for Innovation to Implementation at the Department of Veterans Affairs Health Care System, in Palo Alto, Calif., sought advice from