Genetically testing siblings of newborns with pediatric cancer gene mutations—a targeted screening approach known as sibling cascade testing—would cut related cancer deaths by 50% and lead to overall cost savings compared with usual care, according to a recent study.
“In this study, we estimated that sibling cascade testing would identify approximately 800 siblings with variants [out of approximately 1,600 screened children], avert half of projected cancer deaths before age 20