A retrospective study of cancer patients taking opioid analgesics showed a weak association at most between overall daily opioid consumption and greater severity of self-reported opioid-induced constipation.
Researchers from Massachusetts General Hospital Cancer Center, in Boston, and the University of California, San Diego (UC San Diego), looked to determine whether the total amount of opioids taken would exacerbate symptoms of opioid-induced constipation (OIC) in cancer patients taking