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MARCH 7, 2019

Immunotherapy Can Stall Without Supportive Care


Anaheim, Calif.—A young man came to Memorial Sloan Kettering Cancer Center (MSKCC) looking for help. He had tried multiple treatments for his acute lymphoblastic leukemia (ALL), but a bone marrow biopsy revealed his cancer had returned. So MSKCC doctors tried something new. They took his blood, extracted the T cells, and genetically engineered them to add chimeric antigen receptors (CARs), which direct the T cells to attack the patient's cancer cells.

CAR T-cell therapy is among a wave of