A team of scientists at the Yale Schools of Medicine and Public Health has identified a remdesivir-resistant variant of SARS-CoV-2 in an immunocompromised patient who was being treated with remdesivir (Veklury, Gilead) (Nat Commun 2022 Mar 17. doi:10.1038/s41467-022-29104-y).
The researchers said the discovery raised concerns about the emergence of drug resistance in COVID-19 patients, particularly those who are immunocompromised.
“Because of their immunocompromised state, these